Research - some results

Modeling for cardiac electrophysiology (Inria, IHU Liryc)
My main research topics in Carmen follow two axes:
  • Modeling of subcellular biological mechanisms in cardiomyocytes, and mathematical homogeneization and/or numerical inclusion of these models at the macroscopic scale.
  • Modeling for improvement of cardiac ablation techniques (RF, electroporation) and cardiac stimulation (pacemakers).
 
Electropermeabilization (PhD Inria MONC)
  • Electric field in a cell submitted to high-voltage pulse and change in the membrane surface conductance, where the transmembrane potential difference gets close to a voltage threshold.



  • Qualitative comparison between experimental intake of Propidium Iodide by CHO3 cells (Escoffre et al. 2003) and simulations.

     


  • Influence of lipids diffusion on membrane surface: higher pulse frequencies lead to lower permeability.

Helioseismology (Post-doc @MPS)
  • Propagation of a solar acoustic wave excited by a point source at the north pole. The simulated power spectrum used to generate this video matches observations satisfactorily.